BDBM429724 5-(3-(4-(3,4- difluoro-5- methoxyphenyl) piperidin-1- yl)-3- oxopropyl)-5- methyl- imidazolidine- 2,4-dione::US10550100, Compound 45
SMILES COc1cc(cc(F)c1F)C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O
InChI Key InChIKey=VCBZRHMCWKWBSB-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 429724
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Galapagos
US Patent
Galapagos
US Patent
Affinity DataIC50: >100nMAssay Description:The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by human ADAMTS-5.For the dose res...More data for this Ligand-Target Pair